Longevity research has revealed one proven anti-aging method to slow aging and extend lifespan in mammals: caloric restriction of a nutrient-rich diet. Longevity research has demonstrated this to work in rats and mice, and it is now being studied in monkeys. While no anti-aging therapies have been shown to retard aging, there is a body of scientific evidence suggesting that they have this ability.
For an objective overview of biomedical longevity research and the anti-aging industry, read the written testimony of Robert N. Butler, M.D. (PDF), President and CEO, International Longevity Center - USA and Professor of Geriatrics, Mount Sinai School of Medicine; given before the Senate Special Committee on Aging.